Resumo
Manual therapy commonly begins at the site where pain is reported. This local approach remains clinically useful, but recurrent symptoms may indicate that the painful region does not contain every factor involved in the problem. Fascia forms a continuous and innervated connective tissue network involved in force transmission, tissue sliding, sensory input, and cellular adaptation. Its relationship with neural, vascular, and immune processes offers a possible framework for understanding why local symptoms may be influenced by regional or wider factors. Manual contact may also produce neurophysiological and contextual responses that cannot be attributed to structural tissue change alone. This narrative article examines how fascial continuity, mechanotransduction, biotensegrity, and pain regulation may contribute to clinical reasoning in manual therapy. The proposed approach does not replace local assessment or treatment. Instead, it suggests that the behaviour and recurrence of symptoms should guide the clinician in deciding when a wider, individual evaluation is required.
Referências
Ajimsha, M. S., Shenoy, P. D., & Gampawar, N. (2020). Role of fascial connectivity in musculoskeletal dysfunctions: A narrative review. Journal of Bodywork and Movement Therapies, 24(4), 423–431. https://doi.org/10.1016/j.jbmt.2020.07.020
Arrigoni, A., Rossettini, G., Palese, A., Thacker, M., & Esteves, J. E. (2024). Exploring the role of therapeutic alliance and biobehavioural synchrony in musculoskeletal care: Insights from a qualitative study. Musculoskeletal Science and Practice, 73, Article 103164. https://doi.org/10.1016/j.msksp.2024.103164
Bonanno, M., Papa, G. A., & Calabrò, R. S. (2024). The neurophysiological impact of touch-based therapy: Insights and clinical benefits. Journal of Integrative Neuroscience, 23(12), Article 214. https://doi.org/10.31083/j.jin2312214
Carvalho, G. F., Adamczyk, W. M., Ludes, C. S., Scharbach, R., Jung, A., Karstens, S., Luedtke, K., & Szikszay, T. M. (2025). Perceptions and beliefs of physical therapists regarding the mechanisms of manual therapy. Brazilian Journal of Physical Therapy, 29, Article 101231. https://doi.org/10.1016/j.bjpt.2025.101231
Ernstzen, D. V., Louw, Q. A., & Hillier, S. L. (2017). Clinical practice guidelines for the management of chronic musculoskeletal pain in primary healthcare: A systematic review. Implementation Science, 12, Article 1. https://doi.org/10.1186/s13012-016-0533-0
Fede, C., Petrelli, L., Pirri, C., Neuhuber, W., Tiengo, C., Biz, C., De Caro, R., Schleip, R., & Stecco, C. (2022). Innervation of human superficial fascia. Frontiers in Neuroanatomy, 16, Article 981426. https://doi.org/10.3389/fnana.2022.981426
Garnæs, K. K., Mørkved, S., Tønne, T., Furan, L., Vasseljen, O., & Johannessen, H. H. (2022). Mental health among patients with chronic musculoskeletal pain and its relation to number of pain sites and pain intensity: A cross-sectional study among primary health care patients. BMC Musculoskeletal Disorders, 23, Article 1115. https://doi.org/10.1186/s12891-022-06051-9
George, S. Z. (2017). 21st John H. P. Maley Lecture: Pain management—Road map to revolution. Physical Therapy, 97(2), 217–226. https://doi.org/10.2522/ptj.20160513
Goldenberg, M., Dahan Cohen, R., & Kalichman, L. (2025). Visceral manual therapy as an intervention for musculoskeletal disorders: A scoping review. Journal of Bodywork and Movement Therapies, 45, 724–731. https://doi.org/10.1016/j.jbmt.2025.10.009
Hohenschurz-Schmidt, D., Draper-Rodi, J., Vase, L., Scott, W., McGregor, A., Soliman, N., MacMillan, A., Olivier, A., Cherian, C. A., Corcoran, D., Abbey, H., Freigang, S., Chang, J., Phalip, J., Sørensen, L. N., Delafin, M., Baptista, M., Medforth, N. R., Ruffini, N., . . . Rice, A. S. C. (2023). Blinding and sham control methods in trials of physical, psychological, and self-management interventions for pain (article I): A systematic review and description of methods. Pain, 164(3), 469–484. https://doi.org/10.1097/j.pain.0000000000002723
Hua, W.-W., Feng, X.-Y., Xin, M., & Xie, S. (2026). Efficacy of non-pharmacological interventions on central sensitisation to pain: A systematic review and network meta-analysis. International Journal of Nursing Studies, 182, Article 105607. https://doi.org/10.1016/j.ijnurstu.2026.105607
Huang, H., Chen, L., Lai, Y., Li, W., & Li, J. (2026). Fascia as a functional system in health and disease: From fundamental biology to assessment and targeted interventions. International Journal of Molecular Sciences, 27(13), Article 5871. https://doi.org/10.3390/ijms27135871
Jupin, C., Beltran Aibar, V., & Sarhan, F.-R. (2025). Short-term effects of spinal manual therapy on the nervous system in managing musculoskeletal pain: A systematic review. Journal of Clinical Medicine, 14(11), Article 3830. https://doi.org/10.3390/jcm14113830
Kalichman, L. (2025). Myofascial continuity: Review of anatomical and functional evidence. Journal of Bodywork and Movement Therapies, 45, 569–575. https://doi.org/10.1016/j.jbmt.2025.09.020
Kirkness, K. B., & Scarlata, S. (2026). Understanding fascial tissue on the molecular level—How its unique properties enable adaptation or dysfunction. International Journal of Molecular Sciences, 27(1), Article 160. https://doi.org/10.3390/ijms27010160
Lima, C. R., Martins, D. F., & Reed, W. R. (2020). Physiological responses induced by manual therapy in animal models: A scoping review. Frontiers in Neuroscience, 14, Article 430. https://doi.org/10.3389/fnins.2020.00430
Louw, A., Nijs, J., & Puentedura, E. J. (2017). A clinical perspective on a pain neuroscience education approach to manual therapy. Journal of Manual & Manipulative Therapy, 25(3), 160–168. https://doi.org/10.1080/10669817.2017.1323699
Mo, Y., Jiang, Y., Li, H., Liu, J., Wu, S., Wang, L., Qi, F., & Zhang, X. (2026). Effectiveness of manual therapy on physical and mental health promotion in adults: A systematic review and meta-analysis. Frontiers in Psychology, 17, Article 1815296. https://doi.org/10.3389/fpsyg.2026.1815296
Noten, K., & van Amstel, R. (2024). From muscle–bone concept to the ArthroMyoFascial complex: A pragmatic anatomical concept for physiotherapy and manual therapy. Life, 14(7), Article 799. https://doi.org/10.3390/life14070799
Pedret, C., Peña-Amaro, J., Balius, R., & Järvinen, T. (2025). Histological definition of skeletal muscle injury: A guide to nomenclature along the connective tissue sheath/structure. Sports Medicine, 55, 1061–1065. https://doi.org/10.1007/s40279-024-02165-3
Pomarensky, M., Macedo, L., & Carlesso, L. (2022). Management of chronic musculoskeletal pain through a biopsychosocial lens. Journal of Athletic Training, 57(4), 312–318. https://doi.org/10.4085/1062-6050-0521.20
Potekhina, Y. P., Filatova, A. I., Tregubova, E. S., & Mokhov, D. E. (2020). Mechanosensitivity of cells and its role in the regulation of physiological functions and the implementation of physiotherapeutic effects: A review. Sovremennye Tekhnologii v Meditsine, 12(4), 77–87. https://doi.org/10.17691/stm2020.12.4.10
Rossi, L., Cerritelli, F., Thacker, M., & Esteves, J. E. (2025). The role of sensory attenuation in symptomatic and healthy individuals: A scoping review. Frontiers in Neuroscience, 19, Article 1590127. https://doi.org/10.3389/fnins.2025.1590127
Scarr, G. (2020). Biotensegrity: What is the big deal? Journal of Bodywork and Movement Therapies, 24(1), 134–137. https://doi.org/10.1016/j.jbmt.2019.09.006
Slater, A. M., Barclay, S. J., Granfar, R. M. S., & Pratt, R. L. (2024). Fascia as a regulatory system in health and disease. Frontiers in Neurology, 15, Article 1458385. https://doi.org/10.3389/fneur.2024.1458385
Stecco, A., Bonaldi, L., Fontanella, C. G., Stecco, C., & Pirri, C. (2023). The effect of mechanical stress on hyaluronan fragments’ inflammatory cascade: Clinical implications. Life, 13(12), Article 2277. https://doi.org/10.3390/life13122277
Wilson, A. T., Bishop, M. D., Beneciuk, J. M., Tilley, H. E., Riley, J. L., III, Cruz-Almeida, Y., & Bialosky, J. E. (2023). Expectations affect pain sensitivity changes during massage. Journal of Manual & Manipulative Therapy, 31(2), 84–92. https://doi.org/10.1080/10669817.2022.2118449

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