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Abstract
Objective: To explore canine degenerative myelopathy (CDM), a progressive neurodegenerative condition that affects the quality of life of dogs, emphasizing the importance of early diagnosis and therapeutic approaches. MDC mostly affects adult dogs and causes demyelination of the spinal cord fibers, starting in the thoracolumbar region. Clinical manifestations include paraparesis, ataxia and, in more advanced stages, paralysis. The diagnosis is confirmed after death through histopathological analysis, but the cause is still uncertain. An immune-mediated origin with a possible genetic component is suggested. Treatment is conservative and aims to preserve quality of life, including physical activity, nutritional assistance and medication such as aminocaproic acid and N-acetylcysteine. It is essential to reduce stress and adapt the animal’s environment. Although the response to treatment varies between patients, early interventions can lead to a more favorable prognosis. Cooperation between owners and veterinarians in the management of DCM is crucial, and more studies are needed to understand the mechanisms of the disease, with the aim of creating more efficient and long-lasting treatment strategies.
References
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